DeKuan Chang, PhD（張德寬博士）
Senior Scientist at Torque Therapeutics Inc.
As a scientist, I have a broad background in oncology and immunology, with specific training and expertise in molecular and cellular biology, antibody engineering and optimization, chimeric antigen receptor T cell generation and activation, nanoparticle and drug delivery, and humanized animal model. My research includes translational medicine associated with therapeutic efficacy analysis of anti-cancer drugs, including antibody, nanoparticle, and CAR T cells. Currently, I have worked on engineered antibody and nanoparticles in activation of tumor-specific T cells, developing effective measures of mode of action, cytotoxicity to tumor cells, and establishing proper in vivo study that make it possible to identify anti-tumor immunity and preclinical study.